Wise

Wise can refer to:
 * The Wise Ones, the ancient race that saved the Amerind people
 * D. Wise, a Starfleet commander in the 23rd century

It may also refer to the following production related staff:
 * David Wise, script writer on The Animated Series
 * Douglas E. Wise, assistant director on five of the first six movies
 * Millicent Wise, wife of Robert Wise and an extra in the first movie
 * Ray Wise, an actor who appeared in The Next Generation and Voyager in guest roles
 * Robert Wise, director of Star Trek: The Motion Picture