Alpha Leonis system

The Alpha Leonis system (or Regulus system) was an inhabited planetary system. This system was located in the Alpha Quadrant. There were two known planets that supported life: Regulus III and Regulus V. Notable forms of life in this system included the eel-birds of Regulus V and the Regulan bloodworms. This system was located three hundred light years from the Bajoran system and was located within 90 light years of the Sol system. Its location in the Milky Way Galaxy was depicted on a Federation star chart in 2293. (, production art; ; ; )

In 2154, a Vulcan High Command attack fleet massed in this system in preparation for an abortive preemptive strike against the Andorians. The Regulus system was the closest accessible system that was known to be outside the maximum range of Andorian Imperial Guard listening posts. 

A century later, Christopher Pike once considered retiring and going into business on Regulus or on the Orion colony. 

The location of Regulus in the Milky Way Galaxy was depicted on a Federation star chart of the explored galaxy in 2293. 

In 2366, this system was in need of medical supplies, which were transported there by the USS Enterprise (NCC-1701-D). 

Background information
The association between Alpha Leonis and Regulus is based on official reference material and the real world association. It has not been directly confirmed in canon. According to Star Trek Maps (pg. 29), The Worlds of the Federation (pg. 130) and Startrek.com, Alpha Leonis was the same system as Regulus. Alpha Leonis was the name for Regulus. In the "The Explored Galaxy" star chart, Regulus was located between the Tholian Assembly and Romulus. Both were identified in as being located in the Alpha Quadrant.

According to the Star Trek: Star Charts (pgs. 56,61,62), the Regulus (or Alpha Leonis) system was located in the Beta Quadrant. This was a trinary star system. Regulus A was a B-class star with a magnitude of +1, which was a hundred times brighter than Sol. Regulus B was a M-class star. Regulus C was a K-class star. In 2152, this system was in non-aligned space. Between 2152 and 2378, this system was incorporated into Federation space, and was a destination on the major space lanes.

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Regulanisches System しし座アルファ星系 Alpha Leonis systeem